The main building is compound of the ground floor and five other floors, which house most of the departments and divisions of the hospital.
Ground floor:
- Department of Orthopedics and Traumatology
- Emergency Care Unit and Emergency Rescue Service (SMURD)
- Pharmacy
- Health Care-Associated Infection Prevention and Control Unit
- Integrated outpatient consulting rooms:
- Internal medicine
- Gastroenterology
- Neurology
- Urology
- Cardiology
- Obstetrics-Gynecology
- General Surgery
- Pediatrics
- Oncology
- Laundry room
1st floor:
- Department of Obstetrics and Gynecology (Obstetrics)
- Department of Neonatology
- Department of Pediatrics
- Radiology and Medical Imaging Laboratory
- Sterilization center
- Food and catering unit
2nd floor:
- Department of General Surgery
- Department of Urology
- Department of Anesthesia and Intensive Care
- Transfusion unit
- Operating block
3rd floor:
- Department of Cardiology - Coronary Care Unit
- Department of Obstetrics and Gynecology (Gynecology)
4th floor:
- Department of Internal Medicine
- Department of Gastroenterology
5th floor:
- Department of Neurology
- Department of Oncology
The building of the Department of Otorhinolaryngology as well as that of Rehabilitation, Physical Medicine and Balneology are at 1 km distance from the main building. The seat of the Departments of Ophthalmology, Dermatovenerology and Psychiatry is at 2 km distance from the main building. Another building, at 4 km distance from the main building, houses the Department of Infectious Diseases (including the divisions of HIV/AIDS and that of parasitology) and the Department of Pneumology. In addition, Vlăhița Health Center is situated in the town of Vlăhița, at a 35 km distance from Miercurea Ciuc.
The operating rooms that are indispensable for performing surgical interventions are situated near the surgical departments.